With a variety of natural therapeutic factors (uglekislovodorodnye and radon baths, mud, etc.), Pyatigorsk, gained fame as one of the best resorts for the treatment of musculoskeletal and nervous systems. Even in the prewar period in sanatoria and health resorts as Pyatigorsk Kislovodsk health centers and clinics and balneology institution studied the effect of balneotherapy at disease of the joints. Much attention was paid to the effectiveness of spa therapy in diseases of the musculoskeletal system among workers in various industries. It was shown that radon and sulfide bath to give good results with joint diseases, especially in combination with measured load physiotherapy. In 1933 in Pyatigorsk clinic was organized by the neurological department. Under the guidance of Professor S. Petelin studied the effect of radon baths and uglekisloserovodorodnyh for a neuroinfection and effective methods of spa treatment poliradikulovnerita, poyanichno, sciatica, and polio. In connection with the discovery of highly concentrated radon waters in Pyatigorsk in the mid-sixties began to study their therapeutic action.

It turned out that this method is very effective in alfaterapii sciatica, rheumatoid arthritis and several other diseases. In the same period in the Pyatigorsk Institute clinic for the first time the country had begun to study the effects of spa treatment of encephalitis, arachnoiditis, encephalomyelitis and diencephalic syndrome. Further development of the resort development was marked by neurological problems treating degenerative diseases of the spine. In particular, the proposed new effective methods balneogryazelecheniya discogenic sciatica, using physical therapy facilities. At the same time fully justified resort complex treatment of patients with Brucella lesions of joints, and then with infectious nonspecific (rheumatoid) arthritis and ankylosing spondylitis in Pyatigorsk. Differentiated therapies include uglekisloserovodorodnye, radon baths in combination with physiotherapy, therapeutic exercises. Much attention spa treatment of diseases of musculoskeletal system, central and peripheral nervous system using highly concentrated radon waters Beshtaugorsky newly discovered deposit, paid at the Pyatigorsk health resort. It is of great practical importance to physicians spa facilities. In 1972, Pyatigorsk commissioned fully equipped clinic radon, which introduced new types of radon – suhovozdushnye and four-bath, the vertical extension of the spine in radon water, intestinal procedures, and others. Developed and put into practice methods of using the differentiated radon baths of various concentrations in rheumatoid arthritis, lumbar osteochondrosis and ankylosing spondylitis, vibration disease, gynecological and other diseases.